Read e-book online Advances in Comparative and Environmental Physiology: Volume PDF

By A. D. C. Macknight (auth.), Professor Dr. R. Gilles, Dr. E. K. Hoffmann, Dr. L. Bolis (eds.)

ISBN-10: 3642762263

ISBN-13: 9783642762260

ISBN-10: 364276228X

ISBN-13: 9783642762284

Advances in Compararative and Environmental Physiology is helping biologists, physiologists, and biochemists retain song of the wide literature within the box. offering complete, built-in experiences and sound, severe, and provocative summaries, this sequence is a must for all energetic researchers in environmental and comparative body structure. mobile quantity and osmolality in animals is a good studied subject and this particular quantity within the sequence presents the reader with a radical grounding during this sector of body structure. such as components, the textual content discusses osmolality and quantity keep an eye on when it comes to either inorganic and natural ions which therefore supplies a good evaluation to these operating and drawn to this field.

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Additional resources for Advances in Comparative and Environmental Physiology: Volume and Osmolality Control in Animal Cells

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J Membrane Bioi 91:97-105 Goglein H (1988) Chloride channels in epithelia. Biochim Biophys Acta 947:521-547 Gordon LGM (1988) Electrical transients produced by the toad urinary bladder in response to altered medium osmolality. J PhysioI406:371-392 Grantham JJ, Lowe CM, Dellasega M, Cole BR (1977) Effect of hypotonic medium on K and N a content of proximal tubule cells. Am J PhysioI232:F42-F49 Grinstein S, Rotin D, Mason MJ (1989) Na+/H+ exchange and growth factor-induced cytosolic pH changes. Role in cellular proliferation.

Chloride and bicarbonate may occur in response to cell swelling, mediated by alterations in conductances and/or co-transporters. Solute accumulation following exposure to hyperosmotic media is not seen in all epithelia. When it does occur, it may involve organic solutes and/or inorganic ions, with a variety of secondary active transporters implicated in different epithelia. Responses may reflect contributions of apiCal and/or basolateral pathways. The variety of processes used by the different epithelial preparations to stabilize cell volume tends to lend some credence to the view that volume regulation per se is an important cellular process.

The colonic tumour cell line, T84, serves as a useful preparation for studying this secretion. Under whole cell patch-clamp conditions, these cells swelled over some 5 to 10 min (Worrell et al. 1989). This swelling, attributed to a net gain of solutes from the clamp-pipette, was associated with a marked increase in transmembrane current. Restoration of cell volume, either by increasing medium osmolarity with 50-75 mM sucrose or by decreasing the osmolarity of the filling solution in the pipette by an equivalent amount, returned cell current to initial values.

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Advances in Comparative and Environmental Physiology: Volume and Osmolality Control in Animal Cells by A. D. C. Macknight (auth.), Professor Dr. R. Gilles, Dr. E. K. Hoffmann, Dr. L. Bolis (eds.)

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