By B. W. Hancock, F. E. Neal (auth.), B. W. Hancock MD, DCH, MRCP (eds.)
The evaluate of tumour reaction after therapy is without doubt one of the most crucial demanding situations in Oncology and the image is so usually advanced by means of the consequences of remedy itself. medical overview remains to be through some distance an important approach to review at our disposal yet there's expanding dependence on investigations of every kind as indices of reaction. This depen dence might be lost if irrelevant investigations are pursued and we now have attempted to emphasize during this booklet the significance of selectivity. a few indices of evaluate (e. g. tumour markers, organ imaging) have an essential position to play; others (e. g. histopathology, genetics) are assuming higher impor tance as tumour behaviour turns into higher understood. One topic, Immu nology, remains to be in its infancy as regards tumour follow-up, yet indicates a lot promise in order that a whole account of tumour immunology and traits in immu notherapy has been incorporated. i'm thankful to Dr. Brian Ross for his support with the bankruptcy on Organ Imaging, to the dept of scientific representation for his or her ever-ready co-operation with illustrations and pictures and to overlook Shirley Francis for doing a lot of the typing. B. W. HANCOCK record of members HANCOCK, B. W. , MD, DCH, MRCP, Senior Lecturer in medication, Hon orary advisor general practitioner, Royal Hallamshire & Weston Park Hospitals, Sheffield, U. okay. NEAL, F. E. , KSG, MBChB, FRCR, DMRT, advisor Radiotherapist & Oncologist, Weston Park medical institution, Sheffield, u. okay. POTTER, AM.
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7. Urinary tract Although many tumours of the urinary tract are diagnosed by imaging methods, the management of most tumours, particularly those of the kidney and ureter, is surgical and imaging is largely irrelevant in follow-up of the primary tumour, though it may playa part in the management of its more distant spread. As in the case of the uterine tumours, the staging of prostatic and bladder tumours may be enhanced by the use of CT [28, 29] but its value in the management of these tumours has yet to be evaluated fully.
Clinical appraisal may be difficult. The influence of the use of such techniques on the prognosis has yet to be evaluated. 6. Testis The staging and follow up of testicular tumours is related to the detection of metastatic spread particularly to the abdominal lymph nodes and to the lungs as described above. 7. Urinary tract Although many tumours of the urinary tract are diagnosed by imaging methods, the management of most tumours, particularly those of the kidney and ureter, is surgical and imaging is largely irrelevant in follow-up of the primary tumour, though it may playa part in the management of its more distant spread.
29a, b). 9. Bones The assessment of bone tumours and their progress is generally carried out both by conventional radiological methods and by radio-isotope imaging . Primary bone tumours are relatively uncommon. The radiographic changes include a mass associated with bone destruction, reactive new bone formation and tumour calcification or new bone formation. Response is indicated by a reduction in the volume of any mass present, together with repair and sclerosis of destroyed and infiltrated bone (Figs.
Assessment of Tumour Response by B. W. Hancock, F. E. Neal (auth.), B. W. Hancock MD, DCH, MRCP (eds.)