By Thomas Albrecht, Lars Thorelius, Luigi Solbiati, Luca Cova, Ferdinand Frauscher, M. Hörmann
The worth of ultrasound distinction brokers (USCA) in daily medical perform is determined by the pharmacokinetics, the sign processing, and the contrast-specific imaging modalities. Second-generation USCA, are blood pool brokers that don't leak into the organ tissue to be tested yet stay within the intravascular compartment expanding the Doppler sign amplitude in the course of their dynamic vascular section. profiting from the steadiness in their microbubbles, they could stand up to the acoustic strain of insonation far better than first-generation distinction media, which ends up in an elevated half-life of the agent and, as a result, in a protracted diagnostic window. Concomitant with the advance of distinction brokers, diverse contrast-specific imaging modalities were constructed which, utilized in mix with USCA and a low mechanical index, enable non-stop real-time grey-scale imaging. those fresh technical advancements have opened new probabilities within the use of USCA in numerous symptoms. Written through the world over popular specialists, the contributions amassed during this booklet provide an outline of present and attainable destiny new purposes of USCA in regimen and scientific perform.
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Additional resources for Contrast-enhanced ultrasound in clinical practice: liver, prostate, pancreas, kidney and lymph nodes
Time intensity curves) reported that this technique provides an objective measure for differentiating benign from malignant prostatic tissue. In summary, these results demonstrate the feasibility of US contrast agents to enhance US imaging of prostatic disease. In our opinion, contrast-enhanced US has the potential to play a major role in the diagnostic evaluation of patients undergoing PSA screening for prostate cancer. ■ Background Prostate cancer is the most commonly diagnosed malignancy in men and it is likely to be the most common cause of cancer-related death in men by 2010 .
The present diagnostic strategy for the detection of prostate cancer foresees the use of the so-called sextant biopsy which is considered to be the gold standard . However, What Role for CEUS in Prostate Cancer Examination? sextant biopsy may miss clinically detectable prostate cancer in up to 35% of cases. Therefore, new systematic biopsy approaches have been introduced, which utilize laterally directed cores and a higher number of cores [5-8]. However, limitations still exist because, despite the increase in the number of biopsies (up to 18 or more), cancer detection is not increasing [9-11].
In our opinion, contrast-enhanced US has the potential to play a major role in the diagnostic evaluation of patients undergoing PSA screening for prostate cancer. ■ Background Prostate cancer is the most commonly diagnosed malignancy in men and it is likely to be the most common cause of cancer-related death in men by 2010 . The incidence of prostate cancer is increasing; 24,0000 new cases are estimated in the USA in 2004. Early diagnosis is essential in order to provide definitive treatment and improve patient survival.
Contrast-enhanced ultrasound in clinical practice: liver, prostate, pancreas, kidney and lymph nodes by Thomas Albrecht, Lars Thorelius, Luigi Solbiati, Luca Cova, Ferdinand Frauscher, M. Hörmann