By Chien K.R.
The CT-1 ligand receptor method has no longer been absolutely elucidated. This concept might be complicated through the molecular cloning of the CT-1-specific receptor.
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If the biopsy is to be performed under MR-guidance, all instruments must be fully MR compatible, signiﬁcantly limiting the choice of biopsy equipment. Specimens to be submitted to cytology should be in alcohol, and those submitted to pathology should be in formalin. Microbiology specimens should be placed in culture bottles, if provided; otherwise, submit them, without additives, in a specimen container. Ideally, the biopsy site should be tattooed on the skin with ink to facilitate surgical excision of the entire trajectory should the lesion prove to be a malignant neoplasm.
Whatever the modality selected for guidance during the biopsy, patient positioning is critical (Fig. 3). The patient should be positioned appropriately for the planned biopsy route (compartment anatomy). The route to the lesion should also keep the trajectory of the needle as far as possible from any nearby structures that could be injured. It is also important that the patient be able to maintain this position for the duration of the biopsy. Following localization of the lesion, the access area should be prepped and draped in the usual sterile fashion.
As with any percutaneous biopsy, there is the risk that, despite having obtained seemingly excellent specimens, tissue that is either not representative of the larger mass or that is necrotic may have been harvested. Whether a sampling error (as in the former case) or an inadequate number of cells, either problem may preclude establishment of a diagnosis. To avoid biopsy of necrotic areas in neoplasms with different components, dynamic contrast-enhanced MR imaging can be used to determine the best site for biopsy within a lesion.
CT-1 Receptor by Chien K.R.